منابع مشابه
A model for neuronal competition during development.
We report that developmental competition between sympathetic neurons for survival is critically dependent on a sensitization process initiated by target innervation and mediated by a series of feedback loops. Target-derived nerve growth factor (NGF) promoted expression of its own receptor TrkA in mouse and rat neurons and prolonged TrkA-mediated signals. NGF also controlled expression of brain-...
متن کاملDynamical characteristics common to neuronal competition models.
Models implementing neuronal competition by reciprocally inhibitory populations are widely used to characterize bistable phenomena such as binocular rivalry. We find common dynamical behavior in several models of this general type, which differ in their architecture in the form of their gain functions, and in how they implement the slow process that underlies alternating dominance. We focus on ...
متن کاملNeuronal competition and selection during memory formation.
Competition between neurons is necessary for refining neural circuits during development and may be important for selecting the neurons that participate in encoding memories in the adult brain. To examine neuronal competition during memory formation, we conducted experiments with mice in which we manipulated the function of CREB (adenosine 3',5'-monophosphate response element-binding protein) i...
متن کاملMechanisms for Frequency Control in Neuronal Competition Models
We investigate analytically a firing rate model for a two-population network based on mutual inhibition and slow negative feedback in the form of spike frequency adaptation. Both neuronal populations receive external constant input whose strength determines the system's dynamical state-a steady state of identical activity levels or periodic oscillations or a winner-take-all state of bistability...
متن کاملCompetition for neuronal resources: how hallucinations make themselves heard.
BACKGROUND Hallucinations are perceptions in the absence of a corresponding external sensory stimulus. However, during auditory verbal hallucinations, activation of the primary auditory cortex has been described. AIMS The objective of this study was to investigate whether this activation of the auditory cortex contributes essentially to the character of hallucinations and attributes them to a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 1980
ISSN: 0028-0836,1476-4687
DOI: 10.1038/287585a0